Active NIH Grants
NIH/NINDS, R21NS136070, 06/19/2024 – 05/31/2026
Inhibiting mPGES-1 as a countermeasure to mitigate organophosphate-induced neurotoxicity
PI: Jianxiong Jiang (10% effort)
NIH/NINDS, R01NS100947, 12/08/2023 – 11/30/2028
Inflammatory regulation of epileptogenesis after status epilepticus
PI: Jianxiong Jiang (20% effort)
NIH/NINDS, R61(R33)NS130199, 08/15/2023 – 07/31/2026
EP2 Antagonists for Ischemic Stroke
Contact PI: Jianxiong Jiang (15% effort); MPI: Jiawang Liu
NIH/NINDS, R61(R33)NS124923, 12/01/2021 – 11/30/2024
Targeting TRPC3 Channels for Epileptic Seizures
Contact PI: Jianxiong Jiang (15% effort); MPI: Wei Li
Completed Grants
NIH/NINDS, STTR (Phase I), R41NS135658, 09/20/2023 – 08/31/2024
Developing a selective TRPC3 ion channel inhibitor for epilepsy treatment
UTHSC Contract PI: Jianxiong Jiang; PI: Wei Li, SEAK Therapeutics
NIH/NINDS, R01NS100947, 12/01/2017 – 11/30/2023 (PI: Jiang)
Inflammatory regulation of neurotrophin signaling in epileptogenesis
UTHSC New Grant Support (3 projects), 10/01/2020 – 09/30/2023 (PI: Jiang)
NIH/NINDS, R21NS109687, 01/01/2019 – 12/31/2022 (PI: Jiang)
Targeting prostaglandin receptor EP2 for glioma and associated epilepsy
NIH/NINDS, R00NS082379, 07/01/2015 – 12/31/2019 (PI: Jiang)
Prostaglandin signaling following seizures
Brain & Behavior Research Foundation, 01/15/2014 – 01/14/2018 (PI: Jiang)
(Formerly the National Alliance for Research on Schizophrenia and Depression, NARSAD)
Inflammation in epilepsy-related depression
UC NI/NRC Pilot Grant, 01/01/2016 – 12/31/2016 (PI: Jiang)
(UC Neuroscience Institute and Neurobiology Research Center)
PGE2/EP2 signaling in Parkinson’s disease
NIH (NINDS), K99NS082379, 04/01/2013 – 03/31/2015 (PI: Jiang)
Prostaglandin signaling following seizures
Epilepsy Foundation, 01/01/2012 – 12/31/2012 (PI: Jiang)
Prostaglandin EP2 receptor in brain injury after status epilepticus